Published by Paul Thompson |
Fact-checked against peer-reviewed sources | Updated March 2026
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# Optimized Longevity Stack

Featuring Thorne - pharmaceutical-grade supplements with superior bioavailability. 11 premium formulas for serious longevity optimization.

This stack features exclusively Thorne supplements - trusted by 100+ professional sports teams and recommended by healthcare practitioners. Pharmaceutical-grade quality with enhanced bioavailability for those serious about longevity.

### Thorne CoQ10 (Q-Best 100)

Cellular Energy Production

Crystal-free CoQ10 in a soy oil base - nearly 3x better absorbed than standard forms. Powers mitochondria for heart, brain, and cellular energy. 60 gelcaps.

~$42
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### Thorne Super EPA

Premium Omega-3

Concentrated fish oil with 425mg EPA and 270mg DHA per gelcap. Supports brain, cardiovascular, joint, and skin health. Pharmaceutical-grade purity. 90 gelcaps.

~$38
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### Thorne Curcumin Phytosome 500mg

Anti-Inflammatory

Meriva curcumin bound to phospholipids - 29x more absorbable than standard curcumin. Sustained release for joints, brain, and whole-body inflammation support. 60 capsules.

~$40
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### Thorne Quercetin Phytosome

Senolytic & Antioxidant

50x more absorbable than standard quercetin. Powerful senolytic that helps clear senescent "zombie" cells. Supports immune health and seasonal allergy relief. 60 capsules.

~$32
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### Thorne Berberine 500mg

Metabolic & AMPK Support

Dual-action formula with Phytosome technology. AMPK activator that supports healthy glucose metabolism, heart health, GI function, and cholesterol levels. 60 capsules.

~$35
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### Thorne Magnesium Bisglycinate

Relaxation & Recovery

NSF Certified for Sport. Highly absorbable powdered magnesium for restful sleep, muscle relaxation, heart health, and metabolism. 60 servings per jar.

~$28
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### Thorne Vitamin D + K2 Liquid

Bone & Arterial Health

D3 with MK-7 (long-acting K2). Metered dispenser for precise dosing. Keeps calcium in bones, out of arteries. 600 servings per bottle.

~$28
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### Thorne Basic B Complex

Active Methylated B Vitamins

Pre-methylated forms (methylfolate, methylcobalamin) for those with MTHFR gene variants. No conversion needed - immediately usable by your body. 60 capsules.

~$22
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### Thorne NAC 500mg

Glutathione & Detox

N-Acetylcysteine - precursor to glutathione, your body's master antioxidant. Supports liver detox, respiratory health, and cellular protection. 90 capsules.

~$25
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### Thorne Selenium 200mcg

Antioxidant & Thyroid Support

Essential for glutathione peroxidase - your body's master antioxidant enzyme. Supports thyroid function, immune health, and protects cells from oxidative damage. 60 capsules.

~$15
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### Thorne Creatine

NSF-Certified Performance

NSF Certified for Sport micronized creatine monohydrate. Supports muscle mass, brain energy, and cellular ATP production. 90 servings.

~$35
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## Optional: Complete Your Stack with NAD+ Support

Thorne doesn't make an NAD+ precursor. For comprehensive longevity coverage, consider adding one of these proven options:

### Tru Niagen 300mg (NR)

Patented NAD+ Precursor

Nicotinamide Riboside (NR) - the most clinically-studied NAD+ precursor. Patented Niagen formula shown to boost NAD+ levels by 40-50%. Supports cellular energy, brain, muscle & healthy aging. 30 day supply.

~$58
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### ProHealth NMN Pro 1000 (NMN)

Research-Grade NAD+ Precursor

1000mg Uthever® NMN - the world's first clinically-researched NMN brand. One step closer to NAD+ than NR in the biosynthesis pathway. Preferred by longevity researchers like Dr. David Sinclair. 60 capsules.

~$70
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### ProHealth NADH Pro (NADH)

Direct NAD+ Boost - Budget Option

25mg NADH fast-acting lozenges. NADH is the reduced form of NAD+ - directly boosts cellular energy, memory, focus and ATP production. No conversion needed. 60 lozenges.

~$37
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## Smart Combos: Save Money & Reduce Pills

This 2-in-1 Thorne product combines supplements from this stack, saving you money and simplifying your routine:

### Thorne Omega-3 with CoQ10 (2-in-1)

Replaces: Super EPA + Q-Best 100

450mg EPA + 180mg DHA + 30mg CoQ10 per gelcap. Take 3 daily for 90mg CoQ10 (close to Q-Best 100's dosage). Pharmaceutical-grade purity from sustainably sourced fish. 90 gelcaps.

Saves ~$35 vs buying separately!

~$55
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