Published by Paul Thompson |
Fact-checked against peer-reviewed sources | Updated March 2026
BEST VALUE

# Essential Longevity Stack

Quality longevity basics without breaking the bank. 10 science-backed supplements covering all core needs.

This stack covers the fundamentals: bone health, cellular energy, inflammation control, methylation support, and antioxidant protection. Perfect for beginners or those wanting solid coverage at a sensible price.

### NOW Mega D-3 & MK-7

Bone Health & Immunity

5000 IU Vitamin D3 paired with K2 (MK-7) for proper calcium absorption. Supports immune function, mood, and directs calcium to bones instead of arteries.

~$18
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### NOW NAC Quercetin & Zinc (3-in-1)

Glutathione, Senolytic & Immune

1000mg NAC + 500mg Quercetin + 15mg Zinc. Higher NAC than standalone, plus bonus senolytic quercetin for clearing damaged cells. Covers three bases in one product.

$23.56
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### NOW Magnesium Glycinate

300+ Enzymatic Reactions

Highly absorbable magnesium bound to glycine. Essential for energy production, muscle function, sleep quality, and nervous system support. Most people are deficient.

~$25
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### NOW Omega-3 Fish Oil

Heart & Brain Health

180 EPA / 120 DHA per softgel. Molecularly distilled for purity. Reduces inflammation, supports cardiovascular health and brain function.

~$18
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### NOW Vitamin B-100 Complex

Energy & Methylation

Full spectrum B vitamins for energy metabolism, nervous system function, and methylation - the process that controls gene expression and detoxification.

~$18
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### NOW Copper Glycinate 3mg

Zinc Balance & Structural Health

Albion Copper Glycinate for optimal absorption. Essential to balance zinc supplementation. Supports connective tissue, iron metabolism, nervous system, and energy production.

$7.60
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### NOW CoQ10 100mg

Cellular Energy Production

Pharmaceutical grade CoQ10. Powers your mitochondria - the energy factories in every cell. Essential for heart, brain, and muscles.

~$25
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### NOW Potassium Plus Iodine

Thyroid Function & Metabolism

Supports electrolyte balance and thyroid function. Essential for thyroid hormone production and metabolic regulation. Many people are deficient, especially if avoiding iodized salt. 180 tablets.

$13.05
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### NOW Probiotic-10 25 Billion

Gut Health Foundation

10 probiotic strains for digestive health, immune function, and nutrient absorption. Dairy, soy and gluten free. Your gut is the foundation of all health - 70% of your immune system lives there.

~$22
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### NOW Foods Creatine Monohydrate

Muscle & Brain Energy

Pure creatine monohydrate powder for muscle preservation, cognitive function, and cellular ATP production. The most researched supplement for strength and longevity. 2.2lb (1kg).

$36.38
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## What This Stack Doesn't Cover

This Essential Stack covers the fundamentals of longevity supplementation - the nutrients most people are deficient in and the compounds with the strongest research backing. However, for those seeking a more comprehensive longevity protocol, there are additional compounds worth considering:

#### Taurine

A 2023 study in Science showed taurine supplementation extended lifespan in mice by 10-12%. Levels decline with age, making supplementation potentially valuable for longevity.

#### Glycine / Collagen

Glycine mimics the benefits of methionine restriction - a proven longevity intervention. Also supports sleep quality, connective tissue, and joint health.

#### NMN / NR (NAD+ Precursors)

NAD+ levels decline with age, affecting cellular energy and DNA repair. These precursors help restore youthful NAD+ levels. Available in our Elite Stack.

#### Fisetin & Spermidine

More potent senolytics than quercetin for clearing damaged "zombie" cells. Spermidine activates autophagy - your body's cellular cleanup process. Both in our Elite Stack.

Ready for more advanced longevity support? Explore our Optimized Stack or Elite Stack.

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